Journal article

Brain grey and white matter structural associations with future suicidal ideation and behaviors in adolescent and young adult females with mood disorders

L Colic, LM Villa, MR Dauvermann, LS van Velzen, A Sankar, DA Goldman, P Panchal, JA Kim, S Quatrano, L Spencer, RT Constable, J Suckling, IM Goodyer, L Schmaal, AL van Harmelen, HP Blumberg

Jcpp Advances | Published : 2022

Abstract

Background: To reduce suicide in females with mood disorders, it is critical to understand brain substrates underlying their vulnerability to future suicidal ideation and behaviors (SIBs) in adolescence and young adulthood. In an international collaboration, grey and white matter structure was investigated in adolescent and young adult females with future suicidal behaviors (fSB) and ideation (fSI), and without SIBs (fnonSIB). Methods: Structural (n = 91) and diffusion-weighted (n = 88) magnetic resonance imaging scans at baseline and SIB measures at follow-up on average two years later (standard deviation, SD = 1 year) were assessed in 92 females [age(SD) = 16.1(2.6) years] with bipolar dis..

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University of Melbourne Researchers

Grants

Awarded by Klingenstein Third Generation Foundation


Funding Acknowledgements

Funding National Institute of Mental Health, Grant/Award Numbers: R01MH117601, R01MH121095, R01MH69747, RC1MH088366; American Foundation for Suicide Prevention; AIM Youth Mental Health Foundation; UK Medial Research Council, Grant/Award Number: G0802226; For the Love of Travis Foundation; MQ Brighter Futures Program, Grant/Award Number: MQBFC/2; International Bipolar Foundation; Interdisciplinary Center of Clinical Research of the Medical Faculty Jena; Leiden University Social Safety and Resilience program; Behavioural and Clinical Neuroscience Institute, University of Cambridge; Medical Research Foundation, Grant/Award Number: Emerging leadership award; UK National Institute for Health Research Health Technology Assessment programme, Grant/Award Number: project number 06/05/01; Royal Society Dorothy Hodgkin Fellowship, Grant/Award Number: DH15017; Klingenstein Third Generation Foundation; National Center for Advancing Translational Sciences, Grant/Award Number: UL1TR000142; University of Melbourne Dame Kate Campbell fellowship; NHMRC Career Development Fellowship, Grant/Award Number: 1140764; Suicide Prevention Australia Open Access funding enabled and organized by Projekt DEAL.r No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Availabler No Statement Available